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The enriched phosphopeptide quantity data on a silica-exposed mouse model reported by Wang, Zhang, Liu, et al.

Usage

Silicosis_phos

Format

A data.frame with 21249 rows and 40 variables:

Proteins

The proteins uniprot IDs that phosphopeptide affiliated to

Protein

The first protein uniprot ID

Gene.names

Gene names of the proteins that phosphopeptide affiliated to

Localization.prob

The localization probability of the phosphorylated site

PEP

Posterior error probability of the identification

Score

Andromeda score of peptide identification

Score.for.localization

Andromeda score of the MS/MS spectrum used for calculating the localization score for this site

Amino.acid

The phosphorylated Amino acid

Intensity columns

Raw intensity of phosphopeptide

Reverse

The peptide is identified in the decoy database if marked ('+')

Potential.contaminant

The peptide from a known contaminant protein if marked ('+')

Positions

The possible phosphorylation positions in peptides

Position

The most possible position with phosphorylation

Source

Wang M, Zhang Z, Liu J, et al. Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration. Signal Transduct Target Ther. 2022;7(1):157. doi: 10.1038/s41392-022-00959-3.